WHIST – Wound Healing In Surgery for Trauma is NIHR-HTA funded Randomised Controlled Trial comparing Negative Pressure Wound Therapy (NWPT) dressings for closed surgical wounds with standard dressings in the context of trauma surgery.

The National Institute of Health Research (reference number 14/199/14)
The University of Oxford

The trial is running within the treatment of adult patients having surgical incisions for major trauma to the lower limb. This study is funded by the National Institute of Health Research. The Chief Investigator is Prof Matt Costa, whose research interest is in clinical and cost effectiveness of musculoskeletal interventions. He is Chief Investigator for a series of randomised trials supported by grants from the UK National Institute of Health Research and Musculoskeletal Charities.

As a potential patient click For patients to find more information relating to your treatment, download our Patient Information Sheet and contact the WHIST Trial Team if you have any questions.

Recruitment Start Date July 2016
Recruitment end date January 2018
Follow up end date April 2023

If you are an investigator or involved in the trial's research team you can navigate For the research team pages for further information relating the WHIST Trial.


The following pages give you a full overview of the WHIST trial, along with links to downloading key trial documentation.